Mixed Connective Tissue Disease (MCTD)

Mixed Connective Tissue Disease (MCTD) Mixed Connective Tissue Disease (MCTD) Mixed Connective Tissue Disease (MCTD)
Mixed Connective Tissue Disease (MCTD)

What is Mixed Connective Tissue Disease?

Mixed Connective Tissue Disease (MCTD) is a rare autoimmune disorder that combines features of conditions such as lupus, rheumatoid arthritis, scleroderma, and myositis. It can affect the joints, muscles, skin, lungs, and other organs, with symptoms varying from person to person.

At Niruj Rheumatology & Allergy Clinic, our rheumatologists provide early diagnosis, personalised treatment, and long-term care to help control symptoms, prevent complications, and improve your quality of life.

Key Facts:

  • 80–90% of patients are women
  • Most commonly affects people aged 30–50 years
  • Classified as an overlap syndrome of 3 diseases (Lupus, Scleroderma & Polymyositis)
  • Early diagnosis and proper treatment improve long-term outcomes
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Mixed Connective Tissue Disease

Common Symptoms

Disease at a Glance

Autoimmune Disease

Overlap Autoimmune Disease

Affects Skin, Joints, Muscles & Lungs

Affects Skin, Joints, Muscles & Lungs

More Common in Women

More Common in Women & Pediatric population

Chronic Condition

Chronic Condition

Not Curable, But Manageable
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Not Curable, But Manageable

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Treatable & Manageable

How MCTD Affects the Body

The disease develops gradually and may affect multiple organs before causing persistent symptoms.

Autoimmune Reaction

Autoimmune Reaction

Immune system attacks healthy tissues

Immune system attacks healthy tissues

Inflammation develops

Inflammation develops

Multiple organs get affected

Multiple organs get affected

Persistent symptoms

Persistent symptoms

What Happens in MCTD?

MCTD-Affected Tissue

  • Immune attack on connective tissue
  • Blood vessel spasm (Raynaud’s)
  • Inflammation of muscles & joints
  • Lung tissue involvement
  • Digestive tract dysfunction
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Healthy Tissue

  • Normal immune tolerance
  • Normal blood flow to fingers
  • Pain-free muscles & joints
  • Healthy lung function
  • Normal digestion

Who is at Risk?

More common in women
Young to middle-aged adults
Family history of autoimmune disease
Genetic predisposition
Environmental triggers

When to See a Rheumatologist

Persistent joint pain or swelling

Color changes in fingers

Muscle weakness

Breathlessness

Difficulty swallowing

Lifestyle Tips

  • Protect from cold exposure
  • Stop smoking
  • Eat balanced, small frequent meals
  • Stay physically active
  • Manage stress
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Allergy Immunotherapy Background

Our Specialists

Our team of experienced specialists provides expert care tailored to your unique health needs.

Dr. Anuj Shukla
Dr. Anuj Shukla Head & Consultant Rheumatologist
Qualifications MBBS (NHL MMC), MD (General Medicine, MAMC)
Designation Consultant Rheumatologist
Dr. Kishan Majithiya
Dr. Kishan Majithiya Consultant Rheumatologist & Allergy Specialist
Qualifications MBBS, DNB (Internal Medicine), DM (Clinical Immunology & Rheumatology)
Designation Consultant Rheumatologist and Allergy specialist
Dr. Priyanka Gaur
Dr. Priyanka Gaur Clinical Immunology & Rheumatology
Qualifications BSC, MSC(Biotechnology), PHD(Clinical Immunology)
Designation Clinical Researcher
Dr. Nirav Makwana
Dr. Nirav Makwana Doctor
Qualifications B.H.M.S
Designation Medical Officer
Dr. Divya Nagar
Dr. Divya Nagar Medical Officer
Qualifications B.H.M.S
Designation Medical Officer

Why Patients Trust Niruj Rheumatology & Allergy Clinic

Compassionate, evidence-based rheumatology care focused on long-term wellness.

Evidence-Based Treatment

Internationally accepted protocols tailored to each patient’s condition.

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10+ Years

Specialized Rheumatology Experience

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Compassionate & Long-Term Care

Dedicated management of autoimmune and joint disorders with continuous follow-up for sustained health improvement.

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Accurate & Early Diagnosis

Early detection prevents irreversible joint damage and long-term disability.

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Modern Diagnostic Support

Advanced lab investigations and imaging for precise assessment.
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Transparent Communication

Clear explanation of diagnosis, treatment options, and expected outcomes.

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Patients Managed

Our Treatment Approach

Our Approach to Personalized ANCA-Associated Vasculitis Care

Detailed disease Assessment

Whole-Body Disease Assessment

Complete symptom mapping with organ evaluation for accurate MCTD care planning.

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Precise Diagnostic Evaluation

Comprehensive Autoimmune Profile

Specialized blood investigations and imaging confirm disease activity and overlapping conditions.

02
Individualized Disease Management

Tailored Multi-System Care Strategy

Individualized therapies reduce inflammation, preserve organ function, and improve daily wellbeing.

03
Ongoing Remission Monitoring

Ongoing Health Optimization

Regular reviews help maintain remission, prevent complications, and support lasting quality of life.

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Frequently Asked Questions

Is MCTD curable?
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No, but it is manageable with treatment.
Is it serious?
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It can be, especially if organs like lungs are involved.
Can it affect lungs?
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Yes, lung involvement is common.
Is exercise safe?
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Yes, with guidance.
How often follow-up?
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Every 3–6 months or as advised.
Emergency signs?
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Severe breathlessness, chest pain, or sudden worsening of symptoms.

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Our Approach to Personalized Rheumatology Care

Manage MCTD With Confidence

Receive coordinated treatment designed for complex autoimmune conditions and recovery.

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